Pathophysiology

Zollinger-Ellison Syndrome Gastrin-secreting tumors cause excessive stomach acid production.

Medical Diagnosis

Tests
Secretin stimulation test confirms diagnosis with higher gastrin.
Endoscopy reveals ulcers, hypertrophic gastric folds.

Signs and Symptoms

Abdominal pain and diarrhea.
Weight loss, nausea, and vomiting.

Treatment

Proton pump inhibitors.
Surgical removal of gastrinomas.
Regular monitoring for metastasis.